Health

Users of Zepbound or Mounjaro Had Lower Blood Pressure in Study
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Users of Zepbound or Mounjaro Had Lower Blood Pressure in Study

A study of the weight loss drug tirzepatide showed that people who took it had significantly lower blood pressures after 36 weeks of using the medication.Tirzepatide, made by Eli Lilly, is used to treat Type 2 diabetes, under the brand name Mounjaro, and to treat obesity, under the brand name Zepbound. It is the latest among a new class of weight loss drugs, and its chief competitor is semaglutide, made by Novo Nordisk and sold as Ozempic for diabetes and as Wegovy for weight loss. For both drugs, researchers have been assessing whether they have additional effects that go beyond weight loss.The blood pressure study, supported by Eli Lilly and published on Monday in the journal Hypertension, was part of a larger effort to assess tirzepatide’s effects on weight loss. Researchers had already...
When a Spouse Goes to the Nursing Home
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When a Spouse Goes to the Nursing Home

Even as the signals of approaching dementia became impossible to ignore, Joseph Drolet dreaded the prospect of moving his partner into a long-term care facility.Mr. Drolet, 79, and his beloved Rebecca, 71, both retired lawyers and prosecutors in Atlanta, had been a couple for 33 years, though they retained separate homes. In 2019, she began getting lost while driving, mishandling her finances and struggling with the television remote. The diagnosis — Alzheimer’s disease — came in 2021.Over time, Mr. Drolet moved Rebecca (whose surname he asked to withhold to protect her privacy) into his home. But serving as her round-the-clock caregiver, as she needed help with every daily task, became exhausting and untenable. Rebecca began wandering their neighborhood and “getting dressed in the middle ...
He Hunts Sloppy Scientists. He’s Finding Lots of Prey.
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He Hunts Sloppy Scientists. He’s Finding Lots of Prey.

Are you done hunting scientists for the day?I haven’t had time today. But if I spent a couple of hours reading papers, I’d probably write four or five comments about errors in scientific papers. It’s not hard to find these problems, and it’s not hard to find them at any institution. They’re all out there to find, if anyone wants to read the scientific literature.What motivates you to spend the time to do it?I’m not an anti-vaxxer, I’m not a crank conspiracist or anything like that. I’m a scientist myself, and I care about getting the science right.You focus in part on images that have been mislabeled, or used twice in a paper but as evidence for different things, lazily cut-and-pasted from one spot to another. Is there a simple way for you to tell that an image is wrong?You just look at th...
Runner With Long Covid Creates Flagstaff’s Dream Run Camp
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Runner With Long Covid Creates Flagstaff’s Dream Run Camp

Never one to waste a spare moment, Matt Fitzgerald clambered into the second row of his Mazda CX-90 on a recent weekday morning and cracked open his MacBook so that he could work on another book.Mr. Fitzgerald, 52, is many things — writer, public speaker, coach — but mostly he is prolific. He has written or co-written 34 books, most of them about running, endurance sports and nutrition. He writes early. He writes often. He writes a lot.“Sometimes I do feel like I’m doing B-plus work on a dozen things versus A-plus work on three or four,” he said. “But I am who I am. There’s always a couple of things where I try to give the absolute best of myself at any given time, and I guess that’s enough.”Mr. Fitzgerald has the sort of slim, athletic build that hints at another part of his identity: dis...
Canada Delays Plan to Offer Medically Assisted Death to the Mentally Ill
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Canada Delays Plan to Offer Medically Assisted Death to the Mentally Ill

Canada is postponing a plan to offer people suffering from mental illnesses the option of a medically assisted death, two cabinet ministers said on Monday.The announcement by Mark Holland, the health minister, and Arif Virani, the justice minister, came after a special parliamentary committee looking into the plan concluded that there are not enough doctors, particularly psychiatrists, in the country to assess patients with mental illnesses who want to end their lives and to help them do so.“The system needs to be ready, and we need to get it right,” Mr. Holland told reporters. “It’s clear from the conversations we’ve had that the system is not ready, and we need more time.”Neither minister offered any timeline for the latest extension. Following an earlier delay, the expansion had been sc...
Phones Track Everything but Their Role in Car Wrecks
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Phones Track Everything but Their Role in Car Wrecks

Cellphones can track what we say and write, where we go, what we buy and what we search on the internet. But they still aren’t being used to track one of the biggest public health threats: crashes caused by drivers distracted by the phones.More than a decade after federal and state governments seized on the dangers that cellphone use while driving posed and began enacting laws to stop it, there remains no definitive database of the number of crashes or fatalities caused by cellphone distraction. Safety experts say that current estimates most likely understate a worsening problem.The absence of clear data comes as collisions are rising. Car crashes recorded by the police rose 16 percent from 2020 to 2021, to 16,700 a day from 14,400 a day, according to the National Highway Traffic Safety Ad...
How Worcester Polytechnic Institute Weathered a Spate of Suicides
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How Worcester Polytechnic Institute Weathered a Spate of Suicides

“Were you burned out,” I asked.Her face was flat. “I still am,” she said. “Yeah. Yes, and I still am.” Worcester is famous for the snow dumps it receives in the winter. It has something to do with where the city is in relation to the Appalachian Mountains. The clouds bear down when the temperature drops, and then the snow is relentless and the weather is brutal. All winter, it’s brutal, brutal, brutal, and then somehow, slowly, it’s not anymore. That’s kind of how the end of W.P.I.’s crisis arrived. No one I spoke to could quite explain how they knew that the emergency had subsided; the most they could be sure of was that, one moment in the spring of 2022, they felt intuitively that the last death was behind them. Between the summer 2021 and winter 2022, the faculty existed in a state of s...
Europe Faces a Measles Outbreak
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Europe Faces a Measles Outbreak

Back Story: The pandemic and rising hesitancy slowed immunizations.A false claim in the 1990s that said the combined measles, mumps and rubella vaccine causes autism led to a drop in immunization rates. Public health campaigns later recouped much of that deficit, but the rates again fell during the Covid-19 pandemic, particularly in low-income countries.The measles virus is particularly adept at finding pockets of vulnerability, but outbreaks of other vaccine-preventable diseases may follow, said Dr. Saad Omer, the dean of the O’Donnell School of Public Health at U.T. Southwestern in Dallas.“Measles is usually the canary in the coal mine,” Dr. Omer said. In the United States this year, Philadelphia has recorded nine cases of measles, Washington State confirmed three cases and was investiga...
Top Cancer Center Seeks to Retract or Correct Dozens of Studies
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Top Cancer Center Seeks to Retract or Correct Dozens of Studies

Other papers that Dr. David found to contain irregularities were based on data generated in labs other than those of the Dana-Farber scientists, Dr. Rollins said. He said the institute had started reviewing possible data errors in some of the cases flagged by Dr. David even before he published a blog post about them on Jan. 2, or the Harvard Crimson followed with a story several days later. He also said a review of three of the manuscripts highlighted by Dr. David did not support allegations of data irregularities.“The presence of image discrepancies in a paper is not evidence of an author’s intent to deceive,” he added. “That conclusion can only be drawn after a careful, fact-based examination, which is an integral part of our response.”Dr. David, who earned a doctorate in cellular and mo...
The Heart Surgery That Isn’t as Safe for Older Women
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The Heart Surgery That Isn’t as Safe for Older Women

Last Thanksgiving, Cynthia Mosson had been on her feet all day in her kitchen in Frankfort, Ind., preparing dinner for nine. She was nearly finished — the ham in the oven, the dressing made — when she suddenly felt the need to sit down.“I started hurting in my left shoulder,” said Ms. Mosson, 61. “It got really intense, and it started to go down my left arm.” She grew sweaty and pale and told her family, “I think I’m having a heart attack.”An ambulance sped her to a hospital where doctors confirmed that she had suffered a mild heart attack. They said testing revealed serious blockages in all her coronary arteries and told her, “You’re going to need open-heart surgery,” Ms. Mosson recalled.When such patients head into an operating room, what happens next has a lot to do with their sex, a re...